I am an Internist and Professor of Biomedical Informatics at UC San Diego, where my career has focused on the intersection of clinical care and advanced data science. Having recently served as the inaugural Clinical Research Information Officer (CRIO) for UC San Diego Health, I led the strategic integration of informatics infrastructure to bridge the gap between patient care and discovery through the development of novel clinical research information systems. My research interests center on building secure, scalable data architectures and federated networks that enable multi-site collaboration while preserving patient privacy and institutional autonomy. These efforts are exemplified by my work with UC Research eXchange (UC-ReX), the pSCANNER data network, ENACT, and the creation of the informatics platform for the adaptive ISP2 clinical trial. I have also led the design and development of large-scale public health information systems, including the Maryland Electronic Vital Records Registration System (EVRRS) and the California Integrated Vital Records System (CalIVRS). Cal-IVRS is used by over 3,000 users to perform data collection and vital event registration for 500,000 births and 240,000 deaths annually in California.  A biomedical engineer by training, I am frequently exploring the application of advanced computational methods in medicine. As a Fellow of the American College of Medical Informatics (ACMI), I am committed to pioneering the information science that will underpin the next era of real-world evidence and discovery.